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Mitochondrial one-carbon metabolism maintains redox balance during hypoxia

Mitochondria generate high levels of reactive oxygen species (ROS) to activate pro-tumorigenic signaling pathways. In parallel, the mitochondria must also increase their antioxidant capacity to lower ROS levels and prevent cancer cell death. In this issue, Ye et al. demonstrate that serine catabolis...

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Bibliografiske detaljer
Udgivet i:Cancer Discov
Main Authors: Martínez-Reyes, Inmaculada, Chandel, Navdeep S.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258875/
https://ncbi.nlm.nih.gov/pubmed/25477105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2159-8290.CD-14-1228
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