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Megakaryocytes regulate hematopoietic stem cell quiescence via Cxcl4 secretion
In the bone marrow (BM), hematopoietic stem cells (HSCs) lodge in specialized microenvironments that tightly control their proliferative state to adapt to the varying needs for replenishment of blood cells while also preventing exhaustion(1). All putative niche cells suggested thus far have a non-he...
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| Publicado no: | Nat Med |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258871/ https://ncbi.nlm.nih.gov/pubmed/25326802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.3707 |
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