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Mutant farnesyltransferase beta subunit of Saccharomyces cerevisiae that can substitute for geranylgeranyltransferase type I beta subunit.

The protein farnesyltransferase (PFT) beta-subunit gene of Saccharomyces cerevisiae, DPR1, was randomly mutagenized by PCR to construct a mutant DPR1 gene library on a high-copy plasmid. The library was screened for suppression of the temperature sensitivity conferred by a mutation in the protein ge...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Mitsuzawa, H, Esson, K, Tamanoi, F
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1995
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Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC42588/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7878044/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.5.1704
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