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Vertebrate Hedgehog is secreted on two types of extracellular vesicles with different signaling properties

Hedgehog (Hh) is a secreted morphogen that elicits differentiation and patterning in developing tissues. Multiple proposed mechanisms to regulate Hh dispersion includes lipoprotein particles and exosomes. Here we report that vertebrate Sonic Hedgehog (Shh) is secreted on two types of extracellular-v...

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Bibliografski detalji
Izdano u:Sci Rep
Glavni autori: Vyas, Neha, Walvekar, Ankita, Tate, Dhananjay, Lakshmanan, Vairavan, Bansal, Dhiru, Cicero, Alessandra Lo, Raposo, Graca, Palakodeti, Dasaradhi, Dhawan, Jyotsna
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258658/
https://ncbi.nlm.nih.gov/pubmed/25483805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep07357
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