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Blockade of mTOR Signaling via Rapamycin Combined with Immunotherapy Augments Anti-glioma Cytotoxic and Memory T cells’ Functions
The success of immunotherapeutic approaches targeting Glioblastomamultiforme demand a robust anti-glioma T cell cytotoxic and memory response. Recent evidence suggests that Rapamycin regulates T cell differentiation. Herein, we tested whether administration of Rapamycin could enhance the efficacy of...
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| Publicado no: | Mol Cancer Ther |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258521/ https://ncbi.nlm.nih.gov/pubmed/25256739 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0400 |
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