Clinical utility of a blood-based BRAF V600E mutation assay in melanoma

BRAF inhibitors (BRAFi) have led to clinical benefit in patients with melanoma. The development of a blood-based assay to detect and quantify BRAF levels in these patients has diagnostic, prognostic, and predictive capabilities that could guide treatment decisions. Blood BRAF(V600E) detection and qu...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Panka, David J, Buchbinder, Elizabeth, Giobbie-Hurder, Anita, Schalck, Aislyn P, Montaser-Kouhsari, Laleh, Sepehr, Alireza, Lawrence, Donald P., McDermott, David F., Cohen, Rachel, Carlson, Alexander, Wargo, Jennifer A, Merritt, Ryan, Seery, Virginia J., Hodi, F. Stephen, Gunturi, Anasuya, Fredrick, Dennie, Atkins, Michael B., Iafrate, A. John, Flaherty, Keith T., Mier, James W, Sullivan, Ryan J
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258469/
https://ncbi.nlm.nih.gov/pubmed/25319388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-14-0349
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