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Biomechanical forces in the skeleton and their relevance to bone metastasis: biology and engineering considerations

Bone metastasis represents the leading cause of breast cancer related-deaths. However, the effect of skeleton-associated biomechanical signals on the initiation, progression, and therapy response of breast cancer bone metastasis is largely unknown. This review seeks to highlight possible functional...

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Detalhes bibliográficos
Publicado no:Adv Drug Deliv Rev
Main Authors: Lynch, Maureen, Fischbach, Claudia
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258455/
https://ncbi.nlm.nih.gov/pubmed/25174311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.addr.2014.08.009
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