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Biomechanical forces in tissue engineered tumor models

Solid tumors are complex three-dimensional (3D) networks of cancer and stromal cells within a dynamic extracellular matrix. Monolayer cultures fail to recapitulate the native microenvironment and therefore are poor candidates for pre-clinical drug studies and studying pathways in cancer. The tissue...

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Detalhes bibliográficos
Publicado no:Curr Opin Biomed Eng
Main Authors: Chim, Letitia K, Mikos, Antonios G
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6162057/
https://ncbi.nlm.nih.gov/pubmed/30276358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cobme.2018.03.004
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