c-Abl Modulates Tumor Cell Sensitivity to Antibody-Dependent Cellular Cytotoxicity (ADCC)

Monoclonal antibodies can modulate cancer cell signal transduction and recruit antitumor immune effector mechanisms – including antibody-dependent cellular cytotoxicity (ADCC). Although several clinically effective antibodies can promote ADCC, therapeutic resistance is common. We hypothesized that o...

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Bibliographic Details
Published in:Cancer Immunol Res
Main Authors: Murray, Joseph C., Aldeghaither, Dalal, Wang, Shangzi, Nasto, Rochelle E., Jablonski, Sandra A., Tang, Yong, Weiner, Louis M.
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258447/
https://ncbi.nlm.nih.gov/pubmed/25300860
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0083
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