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c-Abl Modulates Tumor Cell Sensitivity to Antibody-Dependent Cellular Cytotoxicity (ADCC)
Monoclonal antibodies can modulate cancer cell signal transduction and recruit antitumor immune effector mechanisms – including antibody-dependent cellular cytotoxicity (ADCC). Although several clinically effective antibodies can promote ADCC, therapeutic resistance is common. We hypothesized that o...
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Veröffentlicht in: | Cancer Immunol Res |
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Hauptverfasser: | , , , , , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
2014
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258447/ https://ncbi.nlm.nih.gov/pubmed/25300860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/2326-6066.CIR-14-0083 |
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