Th17-biased RORγt Transgenic Mice Become Susceptible to a Viral Model for Multiple Sclerosis

In a viral model for multiple sclerosis (MS), Theiler’s murine encephalomyelitis virus-induced demyelinating disease (TMEV-IDD), both immune-mediated tissue damage (immunopathology) and virus persistence have been shown to cause pathology. T helper (Th) 17 cells are a Th cell subset, whose different...

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Bibliographische Detailangaben
Veröffentlicht in:Brain Behav Immun
Hauptverfasser: Martinez, Nicholas E., Sato, Fumitaka, Kawai, Eiichiro, Omura, Seiichi, Yoh, Keigyou, Takahashi, Satoru, Tsunoda, Ikuo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258441/
https://ncbi.nlm.nih.gov/pubmed/25046854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbi.2014.07.008
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