The cyanobacterial lectin scytovirin displays potent in vitro and in vivo activity against Zaire Ebola virus

The cyanobacterial lectin scytovirin (SVN) binds with high affinity to mannose-rich oligosaccharides on the envelope glycoprotein (GP) of a number of viruses, blocking entry into target cells. In this study, we assessed the ability of SVN to bind to the envelope GP of Zaire Ebola virus (ZEBOV) and i...

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Publicat a:Antiviral Res
Autors principals: Garrison, Aura R., Giomarelli, Barbara G., Lear-Rooney, Calli M., Saucedo, Carrie J., Yellayi, Srikanth, Krumpe, Lauren R.H., Rose, Maura, Paragas, Jason, Bray, Mike, Olinger, Gene G., McMahon, James B., Huggins, John, O’Keefe, Barry R.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258435/
https://ncbi.nlm.nih.gov/pubmed/25265598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.antiviral.2014.09.012
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