Integration of Genomic Data Enables Selective Discovery of Breast Cancer Drivers

Identifying driver genes in cancer remains a crucial bottleneck in therapeutic development and basic understanding of the disease. We developed Helios, a novel algorithm that integrates genomic data from primary tumors with data from functional RNAi screens to pinpoint driver genes within large recu...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Sanchez-Garcia, Félix, Villagrasa, Patricia, Matsui, Junji, Kotliar, Dylan, Castro, Verónica, Akavia, Uri-David, Chen, Bo-Juen, Saucedo-Cuevas, Laura, Barrueco, Ruth Rodriguez, Llobet-Navas, David, Silva, Jose M., Pe’er, Dana
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258423/
https://ncbi.nlm.nih.gov/pubmed/25433701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2014.10.048
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