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CD28-CD80 interactions control regulatory T cell motility and immunological synapse formation(,)

Regulatory T cells (Tregs) are essential for tolerance to self and environmental antigens, acting in part by downmodulating costimulatory molecules on the surface of dendritic cells (DCs) and altering naïve CD4 T cell-DC interactions. Here, we show that Tregs form stable conjugates with DCs before,...

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Bibliographic Details
Published in:J Immunol
Main Authors: Thauland, Timothy J., Koguchi, Yoshinobu, Dustin, Michael L., Parker, David C.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258405/
https://ncbi.nlm.nih.gov/pubmed/25355918
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1401752
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