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Wnt signaling induces gene expression of factors associated with bone destruction in lung and breast cancer
Parathyroid hormone-related protein (PTHrP) is an important regulator of bone destruction in bone metastatic tumors. Transforming growth factor-beta (TGF-β) stimulates PTHrP production in part through the transcription factor Gli2, which is regulated independent of the Hedgehog signaling pathway in...
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| Publicado no: | Clin Exp Metastasis |
|---|---|
| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4258192/ https://ncbi.nlm.nih.gov/pubmed/25359619 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10585-014-9682-1 |
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