Polymorphisms of asparaginase pathway and asparaginase-related complications in children with acute lymphoblastic leukemia

PURPOSE: Asparaginase is a standard and critical component in the therapy of childhood acute lymphoblastic leukemia (ALL), but it is also associated with several toxicities. EXPERIMENTAL DESIGN: We recently reported the results of an association study between asparaginase pathway genes and event fre...

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Veröffentlicht in:Clin Cancer Res
Hauptverfasser: Tanfous, Mohsen Ben, Sharif-Askari, Bahram, Ceppi, Francesco, Laaribi, Haithem, Gagné, Vincent, Rousseau, Julie, Labuda, Malgorzata, Silverman, Lewis B., Sallan, Stephen E., Neuberg, Donna, Kutok, Jeffery L., Sinnett, Daniel, Laverdière, Caroline, Krajinovic, Maja
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4258187/
https://ncbi.nlm.nih.gov/pubmed/24907114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-0508
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