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Immunomodulation of human intestinal T cells by the synthetic CD80 antagonist RhuDex®
Deregulated activation of mucosal lamina propria T cells plays a central role in the pathogenesis of intestinal inflammation. One of the means to attenuate T cell activation is by blocking the CD28/CD80 co-stimulatory pathway. Here we investigate RhuDex®, a small molecule that binds to human CD80, f...
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| Publicado no: | Immun Inflamm Dis |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BlackWell Publishing Ltd
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257762/ https://ncbi.nlm.nih.gov/pubmed/25505551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/iid3.34 |
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