Inhibition of B7-1 (CD80) by RhuDex(®) reduces lipopolysaccharide-mediated inflammation in human atherosclerotic lesions

BACKGROUND: Atherosclerosis is based on a chronic inflammatory process including the innate and adaptive immune response. Costimulatory molecules and their receptors provide decisive signals for antigen-specific cell activation. The contribution of B7-related pathways to atherosclerosis has hardly b...

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Bibliografske podrobnosti
Main Authors: Doesch, Andreas O, Zhao, Li, Gleissner, Christian A, Akhavanpoor, Mohammadreza, Rohde, David, Okuyucu, Deniz, Hakimi, Maani, Dengler, Thomas J, Katus, Hugo A, Erbel, Christian
Format: Artigo
Jezik:Inglês
Izdano: Dove Medical Press 2014
Teme:
Original Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4026407/
https://ncbi.nlm.nih.gov/pubmed/24872677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S59594
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