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Bee Venom Phospholipase A2 Protects against Acetaminophen-Induced Acute Liver Injury by Modulating Regulatory T Cells and IL-10 in Mice

The aim of this study was to investigate the protective effects of phospholipase A2 (PLA2) from bee venom against acetaminophen-induced hepatotoxicity through CD4(+)CD25(+)Foxp3(+) T cells (Treg) in mice. Acetaminophen (APAP) is a widely used antipyretic and analgesic, but an acute or cumulative ove...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Kim, Hyunseong, Keum, Dong June, Kwak, Jung won, Chung, Hwan-Suck, Bae, Hyunsu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257707/
https://ncbi.nlm.nih.gov/pubmed/25478691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114726
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