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Bee venom phospholipase A2 ameliorates motor dysfunction and modulates microglia activation in Parkinson's disease alpha-synuclein transgenic mice

α-Synuclein (α-Syn) has a critical role in microglia-mediated neuroinflammation, which leads to the development of Parkinson's disease (PD). Recent studies have shown that bee venom (BV) has beneficial effects on PD symptoms in human patients or 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPT...

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Enregistré dans:
Détails bibliographiques
Publié dans:Exp Mol Med
Auteurs principaux: Ye, Minsook, Chung, Hwan-Suck, Lee, Chanju, Hyun Song, Joo, Shim, Insop, Kim, Youn-Sub, Bae, Hyunsu
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4973312/
https://ncbi.nlm.nih.gov/pubmed/27388550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emm.2016.49
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