Insight into the Effect of Inhibitor Resistant S130G Mutant on Physico-Chemical Properties of SHV Type Beta-Lactamase: A Molecular Dynamics Study

Bacterial resistance is a serious threat to human health. The production of β-lactamase, which inactivates β-lactams is most common cause of resistance to the β-lactam antibiotics. The Class A enzymes are most frequently encountered among the four β-lactamases in the clinic isolates. Mutations in cl...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Baig, Mohd Hassan, Sudhakar, D. Raja, Kalaiarasan, Ponnusamy, Subbarao, Naidu, Wadhawa, Gulshan, Lohani, Mohtashim, Khan, M Kalim A, Khan, Asad U.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2014
Soggetti:
Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257546/
https://ncbi.nlm.nih.gov/pubmed/25479359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0112456
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi