STAT1-Dependent Signal Integration between IFNγ and TLR4 in Vascular Cells Reflect Pro-Atherogenic Responses in Human Atherosclerosis

Signal integration between IFNγ and TLRs in immune cells has been associated with the host defense against pathogens and injury, with a predominant role of STAT1. We hypothesize that STAT1-dependent transcriptional changes in vascular cells involved in cross-talk between IFNγ and TLR4, reflect pro-a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Chmielewski, Stefan, Olejnik, Adam, Sikorski, Krzysztof, Pelisek, Jaroslav, Błaszczyk, Katarzyna, Aoqui, Cristiane, Nowicka, Hanna, Zernecke, Alma, Heemann, Uwe, Wesoly, Joanna, Baumann, Marcus, Bluyssen, Hans A. R.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4257532/
https://ncbi.nlm.nih.gov/pubmed/25478796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113318
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