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Paused RNA Polymerase II as a Developmental Checkpoint
The textbook view of gene activation is that the rate-limiting step is the interaction of RNA polymerase II (Pol II) with the gene’s promoter. However, studies in a variety of systems, including human embryonic stem cells and the early Drosophila embryo, have begun to challenge this view. There is i...
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| Gepubliceerd in: | Cell |
|---|---|
| Hoofdauteur: | |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
2011
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4257488/ https://ncbi.nlm.nih.gov/pubmed/21565610 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2011.04.021 |
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