A novel genetic locus linked to pro-inflammatory cytokines after virulent H5N1 virus infection in mice

BACKGROUND: Genetic variation in the human population is a key determinant of influenza disease severity. A single nucleotide polymorphism in the antiviral gene IFITM3 was linked to outcomes during the 2009 H1N1 pandemic. To identify variant host genes associated with increased virus replication and...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:BMC Genomics
Main Authors: Boon, Adrianus CM, Williams, Robert W, Sinasac, David S, Webby, Richard J
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2014
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256927/
https://ncbi.nlm.nih.gov/pubmed/25418976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-15-1017
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