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Analysis of cytokine secretion from human plasmacytoid dendritic cells infected with H5N1 or low-pathogenicity influenza viruses

Mechanisms underlying the virulence of H5N1 influenza viruses in humans are poorly understood, though evidence of hyperinflammation and systemic viral replication has been reported. Plasmacytoid dendritic cells (PDCs), a major source of type I interferon, potentially affect host defense against infl...

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Detalhes bibliográficos
Main Authors: Sandbulte, Matthew R., Boon, Adrianus C.M., Webby, Richard J., Riberdy, Janice M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613797/
https://ncbi.nlm.nih.gov/pubmed/18801551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.08.018
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