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Deciphering miRNA transcription factor feed-forward loops to identify drug repurposing candidates for cystic fibrosis

BACKGROUND: Cystic fibrosis (CF) is a fatal genetic disorder caused by mutations in the CF transmembrane conductance regulator (CFTR) gene that primarily affects the lungs and the digestive system, and the current drug treatment is mainly able to alleviate symptoms. To improve disease management for...

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Detalhes bibliográficos
Publicado no:Genome Med
Main Authors: Liu, Zhichao, Borlak, Jürgen, Tong, Weida
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256829/
https://ncbi.nlm.nih.gov/pubmed/25484921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13073-014-0094-2
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