Integrative analysis of gene and miRNA expression profiles with transcription factor–miRNA feed-forward loops identifies regulators in human cancers

We describe here a novel method for integrating gene and miRNA expression profiles in cancer using feed-forward loops (FFLs) consisting of transcription factors (TFs), miRNAs and their common target genes. The dChip-GemiNI (Gene and miRNA Network-based Integration) method statistically ranks computa...

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Detalhes bibliográficos
Main Authors: Yan, Zhenyu, Shah, Parantu K., Amin, Samir B., Samur, Mehmet K., Huang, Norman, Wang, Xujun, Misra, Vikas, Ji, Hongbin, Gabuzda, Dana, Li, Cheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Methods Online
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3458521/
https://ncbi.nlm.nih.gov/pubmed/22645320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks395
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