Small RNA sequencing of extracellular vesicles identifies circulating miRNAs related to inflammation and oxidative stress in HIV patients

Abstract Background Extracellular vesicles (EVs) are nano-sized particles secreted by most cells. EVs carry nucleic acids that hold promise as potential biomarkers in various diseases. Human immunodeficiency virus type 1 (HIV) infects CD4+ T cells and induces immune dysfunction, inflammation, and EV...

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Main Authors: Sukrutha Chettimada, David R. Lorenz, Vikas Misra, Steven M. Wolinsky, Dana Gabuzda
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-11-01
Serier:BMC Immunology
Fag:
Small RNA
MiRNA
Extracellular vesicles
Exosomes
HIV
Inflammation
Online adgang:http://link.springer.com/article/10.1186/s12865-020-00386-5
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