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A Novel and Fast Approach for Population Structure Inference Using Kernel-PCA and Optimization
Population structure is a confounding factor in genome-wide association studies, increasing the rate of false positive associations. To correct for it, several model-based algorithms such as ADMIXTURE and STRUCTURE have been proposed. These tend to suffer from the fact that they have a considerable...
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| Опубликовано в: : | Genetics |
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| Главные авторы: | , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2014
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256762/ https://ncbi.nlm.nih.gov/pubmed/25326237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.114.171314 |
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