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Molecular Signaling Network Motifs Provide a Mechanistic Basis for Cellular Threshold Responses

Background: Increasingly, there is a move toward using in vitro toxicity testing to assess human health risk due to chemical exposure. As with in vivo toxicity testing, an important question for in vitro results is whether there are thresholds for adverse cellular responses. Empirical evaluations ma...

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Библиографические подробности
Опубликовано в: :Environ Health Perspect
Главные авторы: Zhang, Qiang, Bhattacharya, Sudin, Conolly, Rory B., Clewell, Harvey J., Kaminski, Norbert E., Andersen, Melvin E.
Формат: Artigo
Язык:Inglês
Опубликовано: NLM-Export 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256703/
https://ncbi.nlm.nih.gov/pubmed/25117432
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1289/ehp.1408244
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