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A common hypofunctional genetic variant of GPER is associated with increased blood pressure in women

AIMS: Activation of vascular GPER has been linked to vasodepressor effects in animals. However, the significance of GPER regulation on chronic blood pressure control in humans is unknown. METHODS: To examine this question we determined the functional significance of expression of a common missense s...

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Библиографические подробности
Опубликовано в: :Br J Clin Pharmacol
Главные авторы: Feldman, Ross D, Gros, Robert, Ding, Qingming, Hussain, Yasin, Ban, Matthew R, McIntyre, Adam D, Hegele, Robert A
Формат: Artigo
Язык:Inglês
Опубликовано: BlackWell Publishing Ltd 2014
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256633/
https://ncbi.nlm.nih.gov/pubmed/25039431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12471
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