The central nervous system effects of the partial GABA-Aα(2,3)-selective receptor modulator AZD7325 in comparison with lorazepam in healthy males

AIMS: AZD7325 is a novel α(2,3)-subtype-selective partial GABA-A-receptor modulator. This study investigated the pharmacodynamics of single oral doses of AZD7325 2 mg and 10 mg on the central nervous system (CNS) compared with placebo and lorazepam 2 mg. METHODS: This double-blind, randomized, four...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Br J Clin Pharmacol
Main Authors: Chen, Xia, Jacobs, Gabriël, de Kam, Marieke, Jaeger, Judith, Lappalainen, Jaakko, Maruff, Paul, Smith, Mark A, Cross, Alan J, Cohen, Adam, van Gerven, Joop
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2014
Assuntos:
Clinical Trials
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256620/
https://ncbi.nlm.nih.gov/pubmed/24802722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.12413
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados