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SUMOylation by the E3 Ligase TbSIZ1/PIAS1 Positively Regulates VSG Expression in Trypanosoma brucei

Bloodstream form trypanosomes avoid the host immune response by switching the expression of their surface proteins between Variant Surface Glycoproteins (VSG), only one of which is expressed at any given time. Monoallelic transcription of the telomeric VSG Expression Site (ES) by RNA polymerase I (R...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: López-Farfán, Diana, Bart, Jean-Mathieu, Rojas-Barros, Domingo I., Navarro, Miguel
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256477/
https://ncbi.nlm.nih.gov/pubmed/25474309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004545
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