Interleukin-1 and Interferon-γ Orchestrate β-Glucan-Activated Human Dendritic Cell Programming via IκB-ζ Modulation

Recognition of microbial components via innate receptors including the C-type lectin receptor Dectin-1, together with the inflammatory environment, programs dendritic cells (DCs) to orchestrate the magnitude and type of adaptive immune responses. The exposure to β-glucan, a known Dectin-1 agonist an...

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Publicat a:PLoS One
Autors principals: Cardone, Marco, Dzutsev, Amiran K., Li, Hongchuan, Riteau, Nicolas, Gerosa, Franca, Shenderov, Kevin, Winkler-Pickett, Robin, Provezza, Lisa, Riboldi, Elena, Leighty, Robert M., Orr, Selinda J., Steinhagen, Folkert, Wewers, Mark D., Sher, Alan, Anderson, Stephen K., Goldszmid, Romina, McVicar, Daniel W., Lyakh, Lyudmila, Trinchieri, Giorgio
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2014
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256441/
https://ncbi.nlm.nih.gov/pubmed/25474109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114516
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