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TALEN/CRISPR-Mediated eGFP Knock-In Add-On at the OCT4 Locus Does Not Impact Differentiation of Human Embryonic Stem Cells towards Endoderm

Human embryonic stem cells (hESCs) have great promise as a source of unlimited transplantable cells for regenerative medicine. However, current progress on producing the desired cell type for disease treatment has been limited due to an insufficient understanding of the developmental processes that...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Krentz, Nicole A. J., Nian, Cuilan, Lynn, Francis C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2014
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256397/
https://ncbi.nlm.nih.gov/pubmed/25474420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0114275
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