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Selenoprotein H Suppresses Cellular Senescence through Genome Maintenance and Redox Regulation
Oxidative stress and persistent DNA damage response contribute to cellular senescence, a degeneration process critically involving ataxia telangiectasia-mutated (ATM) and p53. Selenoprotein H (SelH), a nuclear selenoprotein, is proposed to carry redox and transactivation domains. To determine the ro...
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| Publicado no: | J Biol Chem |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4256366/ https://ncbi.nlm.nih.gov/pubmed/25336634 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.611970 |
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