E2F Transcription Factor 1 Regulates Cellular and Organismal Senescence by Inhibiting Forkhead Box O Transcription Factors

E2F1 and FOXO3 are two transcription factors that have been shown to participate in cellular senescence. Previous report reveals that E2F1 enhanced cellular senescence in human fibroblast cells, while FOXO transcription factors play against senescence by regulation reactive oxygen species scavenging...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Xie, Qi, Peng, Shengyi, Tao, Li, Ruan, Haihe, Yang, Yanglu, Li, Tie-Mei, Adams, Ursula, Meng, Songshu, Bi, Xiaolin, Dong, Meng-Qiu, Yuan, Zengqiang
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256352/
https://ncbi.nlm.nih.gov/pubmed/25344604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587170
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