E2F Transcription Factor 1 Regulates Cellular and Organismal Senescence by Inhibiting Forkhead Box O Transcription Factors

E2F1 and FOXO3 are two transcription factors that have been shown to participate in cellular senescence. Previous report reveals that E2F1 enhanced cellular senescence in human fibroblast cells, while FOXO transcription factors play against senescence by regulation reactive oxygen species scavenging...

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Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Xie, Qi, Peng, Shengyi, Tao, Li, Ruan, Haihe, Yang, Yanglu, Li, Tie-Mei, Adams, Ursula, Meng, Songshu, Bi, Xiaolin, Dong, Meng-Qiu, Yuan, Zengqiang
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2014
Teme:
Signal Transduction
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256352/
https://ncbi.nlm.nih.gov/pubmed/25344604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.587170
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