Decreasing Mitochondrial Fission Prevents Cholestatic Liver Injury

Mitochondria frequently change their shape through fission and fusion in response to physiological stimuli as well as pathological insults. Disrupted mitochondrial morphology has been observed in cholestatic liver disease. However, the role of mitochondrial shape change in cholestasis is not defined...

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Udgivet i:J Biol Chem
Main Authors: Yu, Tianzheng, Wang, Li, Lee, Hakjoo, O'Brien, Dawn K., Bronk, Steven F., Gores, Gregory J., Yoon, Yisang
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2014
Fag:
Molecular Bases of Disease
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256342/
https://ncbi.nlm.nih.gov/pubmed/25342755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588616
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