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Decreasing Mitochondrial Fission Prevents Cholestatic Liver Injury

Mitochondria frequently change their shape through fission and fusion in response to physiological stimuli as well as pathological insults. Disrupted mitochondrial morphology has been observed in cholestatic liver disease. However, the role of mitochondrial shape change in cholestasis is not defined...

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Dettagli Bibliografici
Pubblicato in:J Biol Chem
Autori principali: Yu, Tianzheng, Wang, Li, Lee, Hakjoo, O'Brien, Dawn K., Bronk, Steven F., Gores, Gregory J., Yoon, Yisang
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256342/
https://ncbi.nlm.nih.gov/pubmed/25342755
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.588616
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