Intramolecular Interactions between the Dbl Homology (DH) Domain and the Carboxyl-terminal region of Myosin II-interacting Guanine Nucleotide Exchange Factor (MyoGEF) Act as an Autoinhibitory Mechanism for the Regulation of MyoGEF Functions

We have reported previously that nonmuscle myosin II-interacting guanine nucleotide exchange factor (MyoGEF) plays an important role in the regulation of cell migration and cytokinesis. Like many other guanine nucleotide exchange factors (GEFs), MyoGEF contains a Dbl homology (DH) domain and a pleck...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wu, Di, Jiao, Meng, Zu, Shicheng, Sollecito, Christopher C., Jimenez-Cowell, Kevin, Mold, Alexander J., Kennedy, Ryan M., Wei, Qize
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2014
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256339/
https://ncbi.nlm.nih.gov/pubmed/25336641
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.607267
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