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Conserved Nutrient Sensor O-GlcNAc Transferase Is Integral to C. elegans Pathogen-Specific Immunity

Discriminating pathogenic bacteria from bacteria used as a food source is key to Caenorhabidits elegans immunity. Using mutants defective in the enzymes of O-linked N-acetylglucosamine (O-GlcNAc) cycling, we examined the role of this nutrient-sensing pathway in the C. elegans innate immune response....

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Bond, Michelle R., Ghosh, Salil K., Wang, Peng, Hanover, John A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256294/
https://ncbi.nlm.nih.gov/pubmed/25474640
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0113231
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