Epigenome-Guided Analysis of the Transcriptome of Plaque Macrophages during Atherosclerosis Regression Reveals Activation of the Wnt Signaling Pathway

We report the first systems biology investigation of regulators controlling arterial plaque macrophage transcriptional changes in response to lipid lowering in vivo in two distinct mouse models of atherosclerosis regression. Transcriptome measurements from plaque macrophages from the Reversa mouse w...

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Vydáno v:PLoS Genet
Hlavní autoři: Ramsey, Stephen A., Vengrenyuk, Yuliya, Menon, Prashanthi, Podolsky, Irina, Feig, Jonathan E., Aderem, Alan, Fisher, Edward A., Gold, Elizabeth S.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256277/
https://ncbi.nlm.nih.gov/pubmed/25474352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004828
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