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Chondrocytes Transdifferentiate into Osteoblasts in Endochondral Bone during Development, Postnatal Growth and Fracture Healing in Mice

One of the crucial steps in endochondral bone formation is the replacement of a cartilage matrix produced by chondrocytes with bone trabeculae made by osteoblasts. However, the precise sources of osteoblasts responsible for trabecular bone formation have not been fully defined. To investigate whethe...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Zhou, Xin, von der Mark, Klaus, Henry, Stephen, Norton, William, Adams, Henry, de Crombrugghe, Benoit
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256265/
https://ncbi.nlm.nih.gov/pubmed/25474590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004820
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