Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used...

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Vydáno v:PLoS Genet
Hlavní autoři: Wartenberg, Anja, Linde, Jörg, Martin, Ronny, Schreiner, Maria, Horn, Fabian, Jacobsen, Ilse D., Jenull, Sabrina, Wolf, Thomas, Kuchler, Karl, Guthke, Reinhard, Kurzai, Oliver, Forche, Anja, d'Enfert, Christophe, Brunke, Sascha, Hube, Bernhard
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256171/
https://ncbi.nlm.nih.gov/pubmed/25474009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004824
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