Microevolution of Candida albicans in Macrophages Restores Filamentation in a Nonfilamentous Mutant

Following antifungal treatment, Candida albicans, and other human pathogenic fungi can undergo microevolution, which leads to the emergence of drug resistance. However, the capacity for microevolutionary adaptation of fungi goes beyond the development of resistance against antifungals. Here we used...

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Bibliographic Details
Published in:PLoS Genet
Main Authors: Wartenberg, Anja, Linde, Jörg, Martin, Ronny, Schreiner, Maria, Horn, Fabian, Jacobsen, Ilse D., Jenull, Sabrina, Wolf, Thomas, Kuchler, Karl, Guthke, Reinhard, Kurzai, Oliver, Forche, Anja, d'Enfert, Christophe, Brunke, Sascha, Hube, Bernhard
Format: Artigo
Language:Inglês
Published: Public Library of Science 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256171/
https://ncbi.nlm.nih.gov/pubmed/25474009
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1004824
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