Deletion of interleukin-6 prevents cardiac inflammation, fibrosis and dysfunction without affecting blood pressure in angiotensin II-high salt-induced hypertension

OBJECTIVE: Inflammation has been proposed as a key component in the development of hypertension and cardiac remodeling associated with different cardiovascular diseases. However, the role of the proinflammatory cytokine interleukin-6 in the chronic stage of hypertension is not well defined. Here, we...

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Pubblicato in:J Hypertens
Autori principali: González, Germán E., Rhaleb, Nour-Eddine, D’ambrosio, Martin A., Nakagawa, Pablo, Liu, Yunhe, Leung, Pablo, Dai, Xiangguo, Yang, Xiao-Ping, Peterson, Edward L., Carretero, Oscar A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256143/
https://ncbi.nlm.nih.gov/pubmed/25304471
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/HJH.0000000000000358
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