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Solid Phase Synthesis of 1,3,4-oxadiazin-5 (6R)-one and 1,3,4-oxadiazol-2-one Scaffolds from Acyl Hydrazides

Solid phase synthesis of 1,3,4-oxadiazin-5(6R)-one and 1,3,4-oxadiazol-2-one scaffolds from resin-bound acyl hydrazides is described. We demonstrate here that the reactions of resin-bound aryl or hetero-aromatic acyl hydrazides with 2-substituted-2-bromoacetic acids and 4-nitrophenyl chloroformate a...

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Detalhes bibliográficos
Publicado no:Org Biomol Chem
Main Authors: Sarma, Bani Kanta, Liu, Xiaodan, Wu, Hao, Gao, Yu, Kodadek, Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256102/
https://ncbi.nlm.nih.gov/pubmed/25354697
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4ob01883d
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