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Live Imaging-Based Model Selection Reveals Periodic Regulation of the Stochastic G1/S Phase Transition in Vertebrate Axial Development

In multicellular organism development, a stochastic cellular response is observed, even when a population of cells is exposed to the same environmental conditions. Retrieving the spatiotemporal regulatory mode hidden in the heterogeneous cellular behavior is a challenging task. The G1/S transition o...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS Comput Biol
Hauptverfasser: Sugiyama, Mayu, Saitou, Takashi, Kurokawa, Hiroshi, Sakaue-Sawano, Asako, Imamura, Takeshi, Miyawaki, Atsushi, Iimura, Tadahiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2014
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256085/
https://ncbi.nlm.nih.gov/pubmed/25474567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1003957
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