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Ligand design for Rh(iii)-catalyzed C–H activation: an unsymmetrical cyclopentadienyl group enables a regioselective synthesis of dihydroisoquinolones

We report the regioselective synthesis of dihydroisoquinolones from aliphatic alkenes and O-pivaloyl benzhydroxamic acids mediated by a Rh(iii) precatalyst bearing sterically bulky substituents. While the prototypical Cp* ligand provides product with low selectivity, sterically bulky Cp(t) affords p...

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書誌詳細
出版年:Chem Sci
主要な著者: Hyster, Todd K., Dalton, Derek M., Rovis, Tomislav
フォーマット: Artigo
言語:Inglês
出版事項: Royal Society of Chemistry 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4256080/
https://ncbi.nlm.nih.gov/pubmed/25489470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02590c
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